COPS6 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
COPS6 transfected lysate.
Western Blot
Lane 1: COPS6 transfected lysate ( 36.2 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-COPS6 full-length
Host
Human
Theoretical MW (kDa)
36.2
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-COPS6 antibody (H00010980-B01) by Western Blots.
SDS-PAGE Gel
COPS6 transfected lysate.
Western Blot
Lane 1: COPS6 transfected lysate ( 36.2 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — COPS6
Entrez GeneID
10980GeneBank Accession#
NM_006833Protein Accession#
NP_006824Gene Name
COPS6
Gene Alias
CSN6, MOV34-34KD
Gene Description
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq
Other Designations
COP9 signalosome subunit 6|COP9 subunit 6 (MOV34 homolog, 34 kD)|H_NH0506M12.12|MOV34 homolog, 34 kD
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