COPS6 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of COPS6 expression in transfected 293T cell line (H00010980-T01) by COPS6 MaxPab polyclonal antibody.
Lane 1: COPS6 transfected lysate(35.97 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human COPS6 protein.
Immunogen
COPS6 (NP_006824.2, 1 a.a. ~ 327 a.a) full-length human protein.
Sequence
MAAAAAAAAATNGTGGSSGMEVDAAVVPSVMACGVTGSVSVALHPLVILNISDHWIRMRSQEGRPVQVIGALIGKQEGRNIEVMNSFELLSHTVEEKIIIDKEYYYTKEEQFKQVFKELEFLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTDLPVSVFESVIDIINGEATMLFAELTYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQHSAIKMLHSRVKLILEYVKASEAGEVPFNHEILREAYALCHCLPVLSTDKFKTDFYDQCNDVGLMAYLGTITKTCNTMNQFVNKFNVLYDRQGIGRRMRGLFF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of COPS6 expression in transfected 293T cell line (H00010980-T01) by COPS6 MaxPab polyclonal antibody.
Lane 1: COPS6 transfected lysate(35.97 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — COPS6
Entrez GeneID
10980GeneBank Accession#
NM_006833.4Protein Accession#
NP_006824.2Gene Name
COPS6
Gene Alias
CSN6, MOV34-34KD
Gene Description
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq
Other Designations
COP9 signalosome subunit 6|COP9 subunit 6 (MOV34 homolog, 34 kD)|H_NH0506M12.12|MOV34 homolog, 34 kD
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