SF3A3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SF3A3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SF3A3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SF3A3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SF3A3
Entrez GeneID
10946GeneBank Accession#
SF3A3Gene Name
SF3A3
Gene Alias
PRP9, PRPF9, SAP61, SF3a60
Gene Description
splicing factor 3a, subunit 3, 60kDa
Omim ID
605596Gene Ontology
HyperlinkGene Summary
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. [provided by RefSeq
Other Designations
OTTHUMP00000004730|pre-mRNA splicing factor SF3a (60kD)|spliceosome associated protein 61|splicing factor 3a, subunit 3
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Interactome
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