MSL3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MSL3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MSL3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MSL3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MSL3
Entrez GeneID
10943GeneBank Accession#
MSL3Gene Name
MSL3
Gene Alias
DKFZp586J1822, MSL3L1
Gene Description
male-specific lethal 3 homolog (Drosophila)
Omim ID
300609Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear protein and has similarity to drosophila male-specific lethal-3 gene. The drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus this encoded protein is thought to play a similar function in chromatin remodeling and transcriptional regulation. This gene has been found to undergo X inactivation. There are four alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000022911|OTTHUMP00000022912|drosophila MSL3-like 1|male-specific lethal 3-like 1
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