FASTK monoclonal antibody (M02), clone 2B7
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of FASTK expression in transfected 293T cell line by FASTK monoclonal antibody (M02), clone 2B7.
Lane 1: FASTK transfected lysate(61.104 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of monoclonal antibody to FASTK on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (35.42 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FASTK.
Immunogen
FASTK (NP_006703, 67 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KWGDRPVGGGPSAGPVQGLQRLLEQAKSPGELLRWLGQNPSKVRAHHYSVALRRLGQLLGSRPRPPPVEQVTLQDLSQLIIRNCPSFD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FASTK expression in transfected 293T cell line by FASTK monoclonal antibody (M02), clone 2B7.
Lane 1: FASTK transfected lysate(61.104 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to FASTK on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — FASTK
Entrez GeneID
10922GeneBank Accession#
NM_006712Protein Accession#
NP_006703Gene Name
FASTK
Gene Alias
FAST
Gene Description
Fas-activated serine/threonine kinase
Omim ID
606965Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq
Other Designations
FAST kinase
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Interactome
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Disease
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