COPS8 monoclonal antibody (M04), clone 2G8
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of COPS8 expression in transfected 293T cell line by COPS8 monoclonal antibody (M04), clone 2G8.
Lane 1: COPS8 transfected lysate(23.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (48.73 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant COPS8.
Immunogen
COPS8 (AAH03090, 1 a.a. ~ 209 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPVAVMAESAFSFKKLLDQCENQELEAPGGIATPPVYGQLLALYLLHNDMNNARYLWKRIPPAIKSANSELGGIWSVGQRIWQRDFPGIYTTINAHQWSETVQPIMEALRDATRRRAFALVSQAYTSIIADDFAAFVGLPVEEAVKGILEQGWQADSTTRMVLPRKPVAGALDVSFNKFIPLSEPAPVPPIPNEQQLARLTDYVAFLEN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (48.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of COPS8 expression in transfected 293T cell line by COPS8 monoclonal antibody (M04), clone 2G8.
Lane 1: COPS8 transfected lysate(23.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — COPS8
Entrez GeneID
10920GeneBank Accession#
BC003090Protein Accession#
AAH03090Gene Name
COPS8
Gene Alias
COP9, CSN8, MGC1297, MGC43256, SGN8
Gene Description
COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
COP9 signalosome subunit 8
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