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Last updated: 2016/12/11
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PPARGC1A (Human) Recombinant Protein (Q01)

  • Catalog # : H00010891-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human PPARGC1A partial ORF ( NP_037393, 689 a.a. - 798 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • TRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPASTKSKYDSLDFDSLLKEAQRSLRR
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 37.84
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00010891-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Gene Name:
  • PPARGC1A
  • Gene Alias:
  • LEM6,PGC-1(alpha),PGC-1v,PGC1,PGC1A,PPARGC1
  • Gene Description:
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
  • Gene Summary:
  • The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000123372,PPAR gamma coactivator variant form,PPAR gamma coactivator-1,ligand effect modulator-6,peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
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