ACTL7A 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
ACTL7A transfected lysate.
Western Blot
Lane 1: ACTL7A transfected lysate ( 48.6 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ACTL7A full-length
Host
Human
Theoretical MW (kDa)
48.6
Interspecies Antigen Sequence
Mouse (85); Rat (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ACTL7A antibody (H00010881-B01) by Western Blots.
SDS-PAGE Gel
ACTL7A transfected lysate.
Western Blot
Lane 1: ACTL7A transfected lysate ( 48.6 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ACTL7A
Entrez GeneID
10881GeneBank Accession#
NM_006687.2Protein Accession#
-Gene Name
ACTL7A
Gene Alias
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Gene Description
actin-like 7A
Omim ID
604303Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known. [provided by RefSeq
Other Designations
actin-like 7-alpha
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