ACTL7B (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of ACTL7B transfected lysate using rabbit polyclonal anti-ACTL7B and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ACTL7B.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (87)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of ACTL7B transfected lysate using rabbit polyclonal anti-ACTL7B and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-ACTL7B.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-ACTL7B (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-ACTL7B (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — ACTL7B
Entrez GeneID
10880Gene Name
ACTL7B
Gene Alias
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Gene Description
actin-like 7B
Omim ID
604304Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq
Other Designations
OTTHUMP00000021867|actin-like 7-beta
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