LILRB1 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of LILRB1 transfected lysate using rabbit polyclonal anti-LILRB1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-LILRB1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-LILRB1 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-LILRB1 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — LILRB1
Entrez GeneID
10859Gene Name
LILRB1
Gene Alias
CD85, CD85J, FLJ37515, ILT2, LIR-1, LIR1, MIR-7, MIR7
Gene Description
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
Omim ID
604811Gene Ontology
HyperlinkGene Summary
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD85 antigen|Ig-like transcript 2|OTTHUMP00000068384|OTTHUMP00000068385|OTTHUMP00000068386|OTTHUMP00000068408|immunoglobulin-like transcript 2|leukocyte Ig-like receptor-1|leukocyte immunoglobulin-like receptor 1|leukocyte immunoglobulin-like receptor sub
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Interactome
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Disease
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