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CYP46A1 (Human) IP-WB Antibody Pair

  • Catalog # : H00010858-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00010858-PW1
    Immunoprecipitation of CYP46A1 transfected lysate using mouse monoclonal anti-CYP46A1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-CYP46A1.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: mouse monoclonal anti-CYP46A1 (300 ug)
    2. Antibody pair for WB: rabbit polyclonal anti-CYP46A1 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Gene Name:
  • CYP46A1
  • Gene Alias:
  • CP46,CYP46
  • Gene Description:
  • cytochrome P450, family 46, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq
  • Other Designations:
  • cholesterol 24-hydroxylase,cytochrome P450, family 46,cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
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