CYP46A1 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of CYP46A1 transfected lysate using mouse monoclonal anti-CYP46A1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-CYP46A1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CYP46A1 transfected lysate using mouse monoclonal anti-CYP46A1 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-CYP46A1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-CYP46A1 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-CYP46A1 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CYP46A1
Entrez GeneID
10858Gene Name
CYP46A1
Gene Alias
CP46, CYP46
Gene Description
cytochrome P450, family 46, subfamily A, polypeptide 1
Omim ID
604087Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq
Other Designations
cholesterol 24-hydroxylase|cytochrome P450, family 46|cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
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Interactome
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Pathway
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Disease
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