RUVBL2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RUVBL2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human RUVBL2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RUVBL2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RUVBL2
Entrez GeneID
10856GeneBank Accession#
RUVBL2Gene Name
RUVBL2
Gene Alias
CGI-46, ECP51, INO80J, REPTIN, RVB2, TIH2, TIP48, TIP49B
Gene Description
RuvB-like 2 (E. coli)
Omim ID
604788Gene Ontology
HyperlinkGene Summary
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq
Other Designations
INO80 complex subunit J|Reptin52|RuvB (E coli homolog)-like 2|RuvB-like 2|TBP-interacting protein, 48-KD|erythrocyte cytosolic protein, 51-KD
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Interactome
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Disease
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