CCL27 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CCL27 full-length ORF ( NP_006655, 1 a.a. - 112 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKGPPTFCSLLLLSLLLSPDPTAAFLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.95
Interspecies Antigen Sequence
Mouse (61)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CCL27
Entrez GeneID
10850GeneBank Accession#
NM_006664.1Protein Accession#
NP_006655Gene Name
CCL27
Gene Alias
ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
Gene Description
chemokine (C-C motif) ligand 27
Omim ID
604833Gene Ontology
HyperlinkGene Summary
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq
Other Designations
CC chemokine ILC|IL-11 Ralpha-locus chemokine|OTTHUMP00000000533|OTTHUMP00000021297|cutaneous T-cell attracting chemokine|skinkine|small inducible cytokine A27|small inducible cytokine subfamily A (Cys-Cys), member 27
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Pathway
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Disease
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