CCL27 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CCL27 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CCL27 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CCL27 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CCL27
Entrez GeneID
10850GeneBank Accession#
CCL27Gene Name
CCL27
Gene Alias
ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
Gene Description
chemokine (C-C motif) ligand 27
Omim ID
604833Gene Ontology
HyperlinkGene Summary
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq
Other Designations
CC chemokine ILC|IL-11 Ralpha-locus chemokine|OTTHUMP00000000533|OTTHUMP00000021297|cutaneous T-cell attracting chemokine|skinkine|small inducible cytokine A27|small inducible cytokine subfamily A (Cys-Cys), member 27
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Pathway
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Disease
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