PDE10A (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human PDE10A partial ORF ( NP_006652, 242 a.a. - 333 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.86
Interspecies Antigen Sequence
Mouse (98); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PDE10A
Entrez GeneID
10846GeneBank Accession#
NM_006661Protein Accession#
NP_006652Gene Name
PDE10A
Gene Alias
FLJ11894, FLJ25677, HSPDE10A
Gene Description
phosphodiesterase 10A
Omim ID
610652Gene Ontology
HyperlinkGene Summary
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).[supplied by OMIM
Other Designations
OTTHUMP00000017586|dJ416F21.1 (phosphodiesterase 10A)|phosphodiesterase 10A1 (PDE10A1)
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Pathway
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Disease
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