PDE10A polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PDE10A.
Immunogen
PDE10A (NP_006652, 242 a.a. ~ 333 a.a) partial recombinant protein with GST tag.
Sequence
GLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (100)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.23 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PDE10A
Entrez GeneID
10846GeneBank Accession#
NM_006661Protein Accession#
NP_006652Gene Name
PDE10A
Gene Alias
FLJ11894, FLJ25677, HSPDE10A
Gene Description
phosphodiesterase 10A
Omim ID
610652Gene Ontology
HyperlinkGene Summary
Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).[supplied by OMIM
Other Designations
OTTHUMP00000017586|dJ416F21.1 (phosphodiesterase 10A)|phosphodiesterase 10A1 (PDE10A1)
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Pathway
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Disease
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