ALDH1L1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ALDH1L1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ALDH1L1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ALDH1L1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ALDH1L1
Entrez GeneID
10840GeneBank Accession#
ALDH1L1Gene Name
ALDH1L1
Gene Alias
DKFZp781N0997, FTHFD
Gene Description
aldehyde dehydrogenase 1 family, member L1
Omim ID
600249Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning. [provided by RefSeq
Other Designations
formyltetrahydrofolate dehydrogenase
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