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GJB6 Pre-design Chimera RNAi

  • Catalog # : H00010804-R01
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens gap junction protein, beta 6 (connexin 30) (GJB6), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006783
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • GJB6
  • Gene Alias:
  • CX30,DFNA3,ED2,EDH,HED
  • Gene Description:
  • gap junction protein, beta 6, 30kDa
  • Gene Summary:
  • Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018096,OTTHUMP00000176870,OTTHUMP00000176871,OTTHUMP00000176872,connexin 30,ectodermal dysplasia 2, hidrotic (Clouston syndrome),gap junction protein, beta 6,gap junction protein, beta 6 (connexin 30)
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