CYSLTR1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CYSLTR1 full-length ORF ( NP_006630.1, 1 a.a. - 337 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
64.9
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CYSLTR1
Entrez GeneID
10800GeneBank Accession#
NM_006639.2Protein Accession#
NP_006630.1Gene Name
CYSLTR1
Gene Alias
CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
Gene Description
cysteinyl leukotriene receptor 1
Omim ID
300201Gene Ontology
HyperlinkGene Summary
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq
Other Designations
LTD4 receptor|OTTHUMP00000023596|cysteinyl leukotriene D4 receptor
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Interactome
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Pathway
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Disease
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