HBS1L 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-HBS1L full-length
Host
Human
Theoretical MW (kDa)
75.35
Interspecies Antigen Sequence
Mouse (88); Rat (88)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-HBS1L antibody (H00010767-B01) by Western Blots.
SDS-PAGE Gel
HBS1L transfected lysate.
Western Blot
Lane 1: HBS1L transfected lysate ( 75.35 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — HBS1L
Entrez GeneID
10767GeneBank Accession#
NM_006620.2Protein Accession#
-Gene Name
HBS1L
Gene Alias
DKFZp686L13262, EF-1a, ERFS, HBS1, HSPC276
Gene Description
HBS1-like (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
Other Designations
HBS1-like|OTTHUMP00000017252
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Interactome
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Disease
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