KDM5B polyclonal antibody (A01)
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More Files
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant KDM5B.
Immunogen
KDM5B (NP_006609, 231 a.a. ~ 319 a.a) partial recombinant protein with GST tag.
Sequence
AKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.9 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — KDM5B
Entrez GeneID
10765GeneBank Accession#
NM_006618Protein Accession#
NP_006609Gene Name
KDM5B
Gene Alias
FLJ10538, FLJ12459, FLJ12491, FLJ16281, FLJ23670, KDM5B, PLU-1, PUT1, RBBP2H1A
Gene Description
jumonji, AT rich interactive domain 1B
Omim ID
605393Gene Ontology
HyperlinkGene Summary
O
Other Designations
OTTHUMP00000038815|RBP2-like|putative DNA/chromatin binding motif|retinoblastoma-binding protein 2, homolog 1A
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Interactomes
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Diseases
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Publication Reference
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Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448.
Bamodu OA, Huang WC, Lee WH, Wu A, Wang LS, Hsiao M, Yeh CT, Chao TY.
BMC Cancer 2016 Feb; 16:160.
Application:WB-Ce, IHC, Human, Breast cancer tissues and cell lines MDA-MB-231, MDA-MB-453 and HS-578 T.
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JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer.
Xiang Y, Zhu Z, Han G, Ye X, Xu B, Peng Z, Ma Y, Yu Y, Lin H, Chen AP, Chen CD.
PNAS 2007 Nov; 104(49):19226.
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Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448.
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