MAP3K2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human MAP3K2 partial ORF ( NP_006600, 111 a.a. - 200 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
HMKSLKILLVINGSTQATNLEPLPSLEDLDNTVFGAERKKRLSIIGPTSRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMEQM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.53
Interspecies Antigen Sequence
Mouse (86); Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAP3K2
Entrez GeneID
10746GeneBank Accession#
NM_006609Protein Accession#
NP_006600Gene Name
MAP3K2
Gene Alias
MEKK2, MEKK2B
Gene Description
mitogen-activated protein kinase kinase kinase 2
Omim ID
609487Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq
Other Designations
MAP/ERK kinase kinase 2|MAPK/ERK kinase kinase 2|MEK kinase 2
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Interactome
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