NFAT5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NFAT5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NFAT5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NFAT5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NFAT5
Entrez GeneID
10725GeneBank Accession#
NFAT5Gene Name
NFAT5
Gene Alias
KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP
Gene Description
nuclear factor of activated T-cells 5, tonicity-responsive
Omim ID
604708Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
NFAT-like protein 1|T cell transcription factor NFAT5|TonE-binding protein|glutamine rich protein H65|nuclear factor of activated T-cells 5|osmotic response element-binding protein|tonicity-responsive enhancer binding protein
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