AP4B1 monoclonal antibody (M03), clone 1B2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant AP4B1.
Immunogen
AP4B1 (NP_006585, 640 a.a. ~ 739 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VAHQQVLPWRGEFHPDTLQMALQVVNIQTIAMSRAGSRPWKAYLSAQDDTGCLFLTELLLEPGNSEMQISVKQNEARTETLNSFISVLETVIGTIEEIKS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91); Rat (90)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged AP4B1 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — AP4B1
Entrez GeneID
10717GeneBank Accession#
NM_006594Protein Accession#
NP_006585Gene Name
AP4B1
Gene Alias
BETA-4
Gene Description
adaptor-related protein complex 4, beta 1 subunit
Omim ID
607245Gene Ontology
HyperlinkGene Summary
The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243).[supplied by OMIM
Other Designations
OTTHUMP00000013725|OTTHUMP00000013730|beta 4 subunit of AP-4
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Interactome
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Pathway
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Disease
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