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EBP Pre-design Chimera RNAi

  • Catalog # : H00010682-R01
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  • Specification
  • Product Description:
  • Homo sapiens emopamil binding protein (sterol isomerase) (EBP), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006579
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • EBP
  • Gene Alias:
  • CDPX2,CHO2,CPX,CPXD
  • Gene Description:
  • emopamil binding protein (sterol isomerase)
  • Gene Summary:
  • The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2; also known as Conradi-Hunermann syndrome). [provided by RefSeq
  • Other Designations:
  • 3-beta-hydroxysteroid-delta-8,delta-7-isomerase,Chondrodysplasia punctata-2, X-linked dominant (Happle syndrome),emopamil-binding protein (sterol isomerase),sterol 8-isomerase
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