CD226 monoclonal antibody (M04), clone 4G8
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant CD226.
Immunogen
CD226 (NP_006557, 21 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VLWHTSVPFAENMSLECVYPSMGILTQVEWFKIGTQQDSIAIFSPTHGMVIRKPYAERVYFLNSTMASNNMTLFFRNASEDDVGYYSCSLYTYPQGTWQKVIQVVQS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (53); Rat (49)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CD226 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — CD226
Entrez GeneID
10666GeneBank Accession#
NM_006566Protein Accession#
NP_006557Gene Name
CD226
Gene Alias
DNAM-1, DNAM1, PTA1, TLiSA1
Gene Description
CD226 molecule
Omim ID
605397Gene Ontology
HyperlinkGene Summary
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq
Other Designations
CD226 antigen|DNAX accessory molecule-1|T lineage-specific activation antigen 1 antigen|adhesion glycoprotein|platelet and T cell activation antigen 1
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Interactomes
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Pathways
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Diseases
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