PMVK monoclonal antibody (M07), clone 2B8
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant PMVK.
Immunogen
PMVK (AAH07694, 1 a.a. ~ 192 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQLENLIEFIRSRL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (85)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (46.86 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PMVK expression in transfected 293T cell line by PMVK monoclonal antibody (M07), clone 2B8.
Lane 1: PMVK transfected lysate(22 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of PMVK transfected lysate using anti-PMVK monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PMVK MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PMVK is 3 ng/ml as a capture antibody.ELISA
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Gene Info — PMVK
Entrez GeneID
10654GeneBank Accession#
BC007694Protein Accession#
AAH07694Gene Name
PMVK
Gene Alias
HUMPMKI, PMK, PMKA, PMKASE
Gene Description
phosphomevalonate kinase
Omim ID
607622Gene Ontology
HyperlinkGene Summary
PMVK (EC 2.7.4.2) is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate as the fifth reaction of the cholesterol biosynthetic pathway.[supplied by OMIM
Other Designations
OTTHUMP00000035546
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Interactomes
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Pathways
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Diseases
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