CAMKK2 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
CAMKK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of CAMKK2 expression in mouse kidney.
Western Blot (Cell lysate)
CAMKK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of CAMKK2 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of CAMKK2 expression in transfected 293T cell line (H00010645-T02) by CAMKK2 MaxPab polyclonal antibody.
Lane 1: CAMKK2 transfected lysate(59.60 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CAMKK2 transfected lysate using anti-CAMKK2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CAMKK2 purified MaxPab mouse polyclonal antibody (B01P) (H00010645-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CAMKK2 protein.
Immunogen
CAMKK2 (NP_705719.2, 1 a.a. ~ 541 a.a) full-length human protein.
Sequence
MSSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSSPRLPRRPTVESHHVSITGMQDCVQLNQYTLKDEIGKGSYGVVKLAYNENDNTYYAMKVLSKKKLIRQAGFPRRPPPRGTRPAPGGCIQPRGPIEQVYQEIAILKKLDHPNVVKLVEVLDDPNEDHLYMVFELVNQGPVMEVPTLKPLSEDQARFYFQDLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFMAPESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPDIAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTRHGAEPLPSEDENCTLVEVTEEEVENSVKHIPSLATVILVKTMIRKRSFGNPFEGSRREERSLSAPGNLLTKQGSEDNLQGTDPPPVGEEEVLL
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (92); Rat (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CAMKK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of CAMKK2 expression in mouse kidney.Western Blot (Cell lysate)
CAMKK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of CAMKK2 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of CAMKK2 expression in transfected 293T cell line (H00010645-T02) by CAMKK2 MaxPab polyclonal antibody.
Lane 1: CAMKK2 transfected lysate(59.60 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CAMKK2 transfected lysate using anti-CAMKK2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CAMKK2 purified MaxPab mouse polyclonal antibody (B01P) (H00010645-B01P). -
Gene Info — CAMKK2
Entrez GeneID
10645GeneBank Accession#
NM_153499.2Protein Accession#
NP_705719.2Gene Name
CAMKK2
Gene Alias
CAMKK, CAMKKB, KIAA0787, MGC15254
Gene Description
calcium/calmodulin-dependent protein kinase kinase 2, beta
Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq
Other Designations
CAMKK beta protein|calcium/calmodulin-dependent protein kinase beta|calcium/calmodulin-dependent protein kinase kinase 2 beta
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Interactome
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Pathway
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Disease
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Publication Reference
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The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells.
Krishan S, Richardson DR, Sahni S.
Biochimica et Biophysica Acta 2016 Sep; 1863(12):2916.
Application：WB, Human, PANC1 cells.
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The Anticancer Agent, Di-2-Pyridylketone 4,4-Dimethyl-3-Thiosemicarbazone (Dp44mT), Up-Regulates the AMPK-Dependent Energy Homeostasis Pathway in Cancer Cells.
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