TRIM16 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human TRIM16 full-length ORF ( NP_006461.3, 1 a.a. - 564 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQGDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
90.4
Interspecies Antigen Sequence
Mouse (77); Rat (76)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TRIM16
Entrez GeneID
10626GeneBank Accession#
NM_006470.3Protein Accession#
NP_006461.3Gene Name
TRIM16
Gene Alias
EBBP
Gene Description
tripartite motif-containing 16
Omim ID
609505Gene Ontology
HyperlinkGene Summary
This gene was identified as an estrogen and anti-estrogen regulated gene in epithelial cells stably expressing estrogen receptor. The protein encoded by this gene contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. The proteins of this family have been reported to be involved in a variety of biological processes including cell growth, differentiation and pathogenesis. Expression of this gene was detected in most tissues. Its function, however, has not yet been determined. [provided by RefSeq
Other Designations
estrogen-responsive B box protein
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Interactome
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Publication Reference
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Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Silvia Martinelli, Elmira A Anderzhanova, Thomas Bajaj, Svenja Wiechmann, Frederik Dethloff, Katja Weckmann, Daniel E Heinz, Tim Ebert, Jakob Hartmann, Thomas M Geiger, Michael Döngi, Kathrin Hafner, Max L Pöhlmann, Lee Jollans, Alexandra Philipsen, Susanne V Schmidt, Ulrike Schmidt, Giuseppina Maccarrone, Valentin Stein, Felix Hausch, Christoph W Turck, Mathias V Schmidt, Anne-Kathrin Gellner, Bernhard Kuster, Nils C Gassen.
Nature Communications 2021 Jul; 12(1):4643.
Application:Pull-Down, Recombinant proteins.
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Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
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