MXD4 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MXD4 full-length
Host
Human
Theoretical MW (kDa)
23.1
Interspecies Antigen Sequence
Mouse (91)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MXD4 antibody (H00010608-B02) by Western Blots.
SDS-PAGE Gel
MXD4 transfected lysate.
Western Blot
Lane 1: MXD4 transfected lysate ( 23.1 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MXD4
Entrez GeneID
10608GeneBank Accession#
NM_006454.2Protein Accession#
NP_006445.1Gene Name
MXD4
Gene Alias
MAD4, MST149, MSTP149, bHLHc12
Gene Description
MAX dimerization protein 4
Gene Ontology
HyperlinkGene Summary
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq
Other Designations
MAD4|Mad4 homolog
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