MXD4 (Human) Recombinant Protein (P01)
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Specification
Product Description
Human MXD4 full-length ORF ( AAH02713, 1 a.a. - 58 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRPPQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.12
Interspecies Antigen Sequence
Mouse (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MXD4
Entrez GeneID
10608GeneBank Accession#
BC002713Protein Accession#
AAH02713Gene Name
MXD4
Gene Alias
MAD4, MST149, MSTP149, bHLHc12
Gene Description
MAX dimerization protein 4
Gene Ontology
HyperlinkGene Summary
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq
Other Designations
MAD4|Mad4 homolog
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