MXD4 purified MaxPab mouse polyclonal antibody (B02P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MXD4 protein.
Immunogen
MXD4 (NP_006445.1, 1 a.a. ~ 209 a.a) full-length human protein.
Sequence
MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDADDHYSLQSGTGGDSGFGPHCRRLGRPALS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (91)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MXD4 expression in transfected 293T cell line (H00010608-T02) by MXD4 MaxPab polyclonal antibody.
Lane 1: MXD4 transfected lysate(22.99 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MXD4
Entrez GeneID
10608GeneBank Accession#
NM_006454.2Protein Accession#
NP_006445.1Gene Name
MXD4
Gene Alias
MAD4, MST149, MSTP149, bHLHc12
Gene Description
MAX dimerization protein 4
Gene Ontology
HyperlinkGene Summary
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq
Other Designations
MAD4|Mad4 homolog
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