CDC42EP3 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human CDC42EP3 partial ORF ( NP_006440, 42 a.a. - 108 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
IHIGKEGQHDVFGDISFLQGNYELLPGNQEKAHLGQFPGHNEFFRANSTSDSVFTETPSPVLKNAIS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.11
Interspecies Antigen Sequence
Mouse (92); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CDC42EP3
Entrez GeneID
10602GeneBank Accession#
NM_006449Protein Accession#
NP_006440Gene Name
CDC42EP3
Gene Alias
BORG2, CEP3, FLJ46903, UB1
Gene Description
CDC42 effector protein (Rho GTPase binding) 3
Omim ID
606133Gene Ontology
HyperlinkGene Summary
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation. [provided by RefSeq
Other Designations
CRIB-containing BORG2 protein|Cdc42 effector protein 3|MSE55-related protein
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