SLCO1B1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SLCO1B1 partial ORF ( NP_006437, 481 a.a. - 570 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.64
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLCO1B1
Entrez GeneID
10599GeneBank Accession#
NM_006446Protein Accession#
NP_006437Gene Name
SLCO1B1
Gene Alias
LST-1, LST1, MGC133282, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6
Gene Description
solute carrier organic anion transporter family, member 1B1
Omim ID
604843Gene Ontology
HyperlinkGene Summary
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq
Other Designations
solute carrier family 21 (organic anion transporter), member 6
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Interactome
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Disease
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