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Last updated: 2016/12/4

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PRPF8 rabbit monoclonal antibody

  • Catalog # : H00010594-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PRPF8 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PRPF8 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PRPF8 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • PRPF8
  • Gene Name:
  • PRPF8
  • Gene Alias:
  • HPRP8,PRP8,PRPC8,RP13
  • Gene Description:
  • PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)
  • Gene Summary:
  • Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. [provided by RefSeq
  • Other Designations:
  • U5 snRNP-specific protein,U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p,apoptosis-regulated protein 1,apoptosis-regulated protein 2,precursor mRNA processing protein,splicing factor Prp8
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