POMT1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human POMT1 partial ORF ( NP_009102.2, 483 a.a. - 580 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LPDWGYRQLEIVGEKLSRGYHGSTVWNVEEHRYGASQEQRERERELHSPAQVDVSRNLSFMARFSELQWRMLALRSDDSEHKYSSSPLEWVTLDTNIA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (85); Rat (85)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — POMT1
Entrez GeneID
10585GeneBank Accession#
NM_007171Protein Accession#
NP_009102.2Gene Name
POMT1
Gene Alias
FLJ37239, LGMD2K, RT
Gene Description
protein-O-mannosyltransferase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000022405|OTTHUMP00000022406|OTTHUMP00000022407
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Interactome
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Pathway
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Disease
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