COLEC10 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human COLEC10 full-length ORF ( NP_006429.1, 1 a.a. - 277 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNGFASLLRRNQFILLVLFLLQIQSLGLDIDSRPTAEVCATHTISPGPKGDDGEKGDPGEEGKHGKVGRMGPKGIKGELGDMGDQGNIGKTGPIGKKGDKGEKGLLGIPGEKGKAGTVCDCGRYRKFVGQLDISIARLKTSMKFVKNVIAGIRETEEKFYYIVQEEKNYRESLTHCRIRGGMLAMPKDEAANTLIADYVAKSGFFRVFIGVNDLEREGQYMFTDNTPLQNYSNWNEGEPSDPYGHEDCVEMLSSGRWNDTECHLTMYFVCEFIKKKK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
57.1
Interspecies Antigen Sequence
Mouse (88); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — COLEC10
Entrez GeneID
10584GeneBank Accession#
NM_006438.2Protein Accession#
NP_006429.1Gene Name
COLEC10
Gene Alias
CLL1, MGC118794, MGC118795
Gene Description
collectin sub-family member 10 (C-type lectin)
Omim ID
607620Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. [provided by RefSeq
Other Designations
collectin 34|collectin liver 1|collectin sub-family member 10
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Interactome
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Publication Reference
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COLEC10 is mutated in 3MC patients and regulates early craniofacial development.
Munye MM, Diaz-Font A, Ocaka L, Henriksen ML, Lees M, Brady A, Jenkins D, Morton J, Hansen SW, Bacchelli C, Beales PL, Hernandez-Hernandez V.
PLoS Genetics 2017 Mar; 13(3):e1006679.
Application：Func, Human, HeLa cells.
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COLEC10 is mutated in 3MC patients and regulates early craniofacial development.
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