GNLY (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human GNLY partial ORF ( NP_006424.2, 46 a.a. - 145 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRLCIPSTGPL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — GNLY
Entrez GeneID
10578GeneBank Accession#
NM_006433Protein Accession#
NP_006424.2Gene Name
GNLY
Gene Alias
519, D2S69E, LAG-2, LAG2, NKG5, TLA519
Gene Description
granulysin
Omim ID
188855Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
T-lymphocyte activation gene 519|lymphocyte-activation gene 2
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Interactome
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Disease
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