GNLY rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GNLY peptide using ARM Technology.
Immunogen
A synthetic peptide of human GNLY is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GNLY peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GNLY
Entrez GeneID
10578GeneBank Accession#
GNLYGene Name
GNLY
Gene Alias
519, D2S69E, LAG-2, LAG2, NKG5, TLA519
Gene Description
granulysin
Omim ID
188855Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
T-lymphocyte activation gene 519|lymphocyte-activation gene 2
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Interactome
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Disease
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