NPC2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-NPC2 full-length
Host
Human
Theoretical MW (kDa)
16.6
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NPC2 antibody (H00010577-D01P) by Western Blots.
SDS-PAGE Gel
NPC2 transfected lysate.
Western Blot
Lane 1: NPC2 transfected lysate ( 16.60 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — NPC2
Entrez GeneID
10577GeneBank Accession#
NM_006432.3Protein Accession#
NP_006423.1Gene Name
NPC2
Gene Alias
HE1, MGC1333, NP-C2
Gene Description
Niemann-Pick disease, type C2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq
Other Designations
epididymal secretory protein|epididymal secretory protein E1|tissue-specific secretory protein
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Interactome
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Disease
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