ARFGEF1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human ARFGEF1 partial ORF ( NP_006412.2, 311 a.a. - 411 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
EVLYDGENHDCEEKPQDIVQNIVEEMVNIVVGDMGEGTTINASADGNIGTIEDGSDSENIQANGIPGTPISVAYTPSLPDDRLSVSSNDTQESGNSSGPSP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.85
Interspecies Antigen Sequence
Mouse (84); Rat (84)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ARFGEF1
Entrez GeneID
10565GeneBank Accession#
NM_006421Protein Accession#
NP_006412.2Gene Name
ARFGEF1
Gene Alias
ARFGEP1, BIG1, D730028O18Rik, DKFZP434L057, P200
Gene Description
ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
Omim ID
604141Gene Ontology
HyperlinkGene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP. It contains a Sec7 domain, which may be responsible for the guanine-nucleotide exchange activity and also the brefeldin A inhibition. [provided by RefSeq
Other Designations
brefeldin A-inhibited guanine nucleotide-exchange protein 1
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