CXCL13 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CXCL13 full-length ORF ( NP_006410.1, 1 a.a. - 109 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
39.1
Interspecies Antigen Sequence
Mouse (47); Rat (43)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CXCL13
Entrez GeneID
10563GeneBank Accession#
NM_006419.1Protein Accession#
NP_006410.1Gene Name
CXCL13
Gene Alias
ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
Gene Description
chemokine (C-X-C motif) ligand 13
Omim ID
605149Gene Ontology
HyperlinkGene Summary
B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq
Other Designations
B-cell chemoattractant|B-cell-attracting chemokine 1|B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)|B-lymphocyte chemoattractant|chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)|small inducible cytokine B subfamily (Cys-X-Cys
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Interactome
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Pathway
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Disease
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Publication Reference
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Activated microglia enhance neurogenesis via trypsinogen secretion.
Nikolakopoulou AM, Dutta R, Chen Z, Miller RH, Trapp BD.
PNAS 2013 May; 110(21):8714.
Application：Array, MS, Recombinant protein.
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Activated microglia enhance neurogenesis via trypsinogen secretion.
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