CXCL13 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CXCL13 protein.
Immunogen
CXCL13 (NP_006410.1, 1 a.a. ~ 109 a.a) full-length human protein.
Sequence
MKFISTSLLLMLLVSSLSPVQGVLEVYYTSLRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQAEWIQRMMEVLRKRSSSTLPVPVFKRKIP
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (47); Rat (43)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CXCL13 expression in transfected 293T cell line (H00010563-T02) by CXCL13 MaxPab polyclonal antibody.
Lane 1: CXCL13 transfected lysate(12.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CXCL13 transfected lysate using anti-CXCL13 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CXCL13 MaxPab mouse polyclonal antibody (B02) (H00010563-B02). -
Gene Info — CXCL13
Entrez GeneID
10563GeneBank Accession#
NM_006419Protein Accession#
NP_006410.1Gene Name
CXCL13
Gene Alias
ANGIE, ANGIE2, BCA-1, BCA1, BLC, BLR1L, SCYB13
Gene Description
chemokine (C-X-C motif) ligand 13
Omim ID
605149Gene Ontology
HyperlinkGene Summary
B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq
Other Designations
B-cell chemoattractant|B-cell-attracting chemokine 1|B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1)|B-lymphocyte chemoattractant|chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)|small inducible cytokine B subfamily (Cys-X-Cys
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Interactome
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Pathway
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Disease
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Publication Reference
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CXCL13 Is Involved in the Lipopolysaccharide-Induced Hyperpermeability of Umbilical Vein Endothelial Cells.
Wen Chen, Yi Wang, Ting Zhou, Yuansheng Xu, Jianwei Zhan, Jinhong Wu.
Inflammation 2020 Oct; 43(5):1789.
Application:Treated, Recombinant protein.
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CXCL13 Is Involved in the Lipopolysaccharide-Induced Hyperpermeability of Umbilical Vein Endothelial Cells.
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