SPTLC1 monoclonal antibody (M09), clone 3D11
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SPTLC1 is 0.3 ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.85 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant SPTLC1.
Immunogen
SPTLC1 (AAH07085, 43 a.a. ~ 143 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TYKLQERSDLTVKEKEELIEEWQPEPLVPPVPKDHPALNYNIVSGPPSHKTVVNGKECINFASFNFLGLLDNPRVKAATLASLKKYGVGTCGPRGFYGTFE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (90)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.85 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SPTLC1 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — SPTLC1
Entrez GeneID
10558GeneBank Accession#
BC007085Protein Accession#
AAH07085Gene Name
SPTLC1
Gene Alias
HSAN, HSAN1, HSN1, LBC1, LCB1, MGC14645, SPT1, SPTI
Gene Description
serine palmitoyltransferase, long chain base subunit 1
Gene Ontology
HyperlinkGene Summary
Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000022810|OTTHUMP00000022811|long chain base biosynthesis protein 1|serine C-palmitoyltransferase|serine palmitoyltransferase subunit 1|serine-palmitoyl-CoA transferase 1
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Interactome
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Pathway
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Disease
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