PRDX4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PRDX4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PRDX4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PRDX4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PRDX4
Entrez GeneID
10549GeneBank Accession#
PRDX4Gene Name
PRDX4
Gene Alias
AOE37-2, PRX-4
Gene Description
peroxiredoxin 4
Omim ID
606506Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq
Other Designations
OTTHUMP00000023056|thioredoxin peroxidase|thioredoxin peroxidase (antioxidant enzyme)
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Interactome
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