DCTN2 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of DCTN2 expression in transfected 293T cell line (H00010540-T02) by DCTN2 MaxPab polyclonal antibody.
Lane 1: DCTN2 transfected lysate(44.20 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DCTN2 protein.
Immunogen
DCTN2 (AAH00718.1, 1 a.a. ~ 401 a.a) full-length human protein.
Sequence
MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DCTN2 expression in transfected 293T cell line (H00010540-T02) by DCTN2 MaxPab polyclonal antibody.
Lane 1: DCTN2 transfected lysate(44.20 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — DCTN2
Entrez GeneID
10540GeneBank Accession#
BC000718Protein Accession#
AAH00718.1Gene Name
DCTN2
Gene Alias
DCTN50, DYNAMITIN, RBP50
Gene Description
dynactin 2 (p50)
Omim ID
607376Gene Ontology
HyperlinkGene Summary
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq
Other Designations
50 kD dynein-associated polypeptide|dynactin 2|dynactin complex 50 kD subunit
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Interactome
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