RNASEH2A purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
RNASEH2A MaxPab polyclonal antibody. Western Blot analysis of RNASEH2A expression in Jurkat.
Western Blot (Cell lysate)
RNASEH2A MaxPab polyclonal antibody. Western Blot analysis of RNASEH2A expression in COLO 320 HSR.
Western Blot (Transfected lysate)
Western Blot analysis of RNASEH2A expression in transfected 293T cell line (H00010535-T01) by RNASEH2A MaxPab polyclonal antibody.
Lane 1: RNASEH2A transfected lysate(32.89 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RNASEH2A on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RNASEH2A protein.
Immunogen
RNASEH2A (NP_006388.2, 1 a.a. ~ 299 a.a) full-length human protein.
Sequence
MDLSELERDNTGRCRLSSPVPAVCRKEPCVLGVDEAGRGPVLGPMVYAICYCPLPRLADLEALKVADSKTLLESERERLFAKMEDTDFVGWALDVLSPNLISTSMLGRVKYNLNSLSHDTATGLIQYALDQGVNVTQVFVDTVGMPETYQARLQQSFPGIEVTVKAKADALYPVVSAASICAKVARDQAVKKWQFVEKLQDLDTDYGSGYPNDPKTKAWLKEHVEPVFGFPQFVRFSWRTAQTILEKEAEDVIWEDSASENQEGLRKITSYFLNEGSQARPRSSHRYFLERGLESATSL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (84)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
RNASEH2A MaxPab polyclonal antibody. Western Blot analysis of RNASEH2A expression in Jurkat.Western Blot (Cell lysate)
RNASEH2A MaxPab polyclonal antibody. Western Blot analysis of RNASEH2A expression in COLO 320 HSR.Western Blot (Transfected lysate)
Western Blot analysis of RNASEH2A expression in transfected 293T cell line (H00010535-T01) by RNASEH2A MaxPab polyclonal antibody.
Lane 1: RNASEH2A transfected lysate(32.89 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to RNASEH2A on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — RNASEH2A
Entrez GeneID
10535GeneBank Accession#
NM_006397Protein Accession#
NP_006388.2Gene Name
RNASEH2A
Gene Alias
AGS4, JUNB, RNASEHI, RNHIA, RNHL
Gene Description
ribonuclease H2, subunit A
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid
Other Designations
ribonuclease H2, large subunit|ribonuclease HI, large subunit
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Interactome
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Pathway
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