CARM1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human CARM1 partial ORF ( NP_954592, 284 a.a. - 381 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHMLHS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CARM1
Entrez GeneID
10498GeneBank Accession#
NM_199141Protein Accession#
NP_954592Gene Name
CARM1
Gene Alias
PRMT4
Gene Description
coactivator-associated arginine methyltransferase 1
Omim ID
603934Gene Ontology
HyperlinkGene Summary
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 [PubMed 11724789]).[supplied by OMIM
Other Designations
coactivator-associated arginine methyltransferase-1|protein arginine N-methyltransferase 4
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Interactome
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Disease
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