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Last updated: 2016/12/4

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UNC13B Pre-design Chimera RNAi

  • Catalog # : H00010497-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens unc-13 homolog B (C. elegans) (UNC13B), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_006377
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • UNC13B
  • Gene Alias:
  • MGC133279,MGC133280,MUNC13,UNC13,Unc13h2,hmunc13
  • Gene Description:
  • unc-13 homolog B (C. elegans)
  • Gene Summary:
  • This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021327,UNC13 (C. elegans)-like,homolog of rat Munc13 (diacylglycerol-binding),unc-13-like
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