CREB3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
CREB3 transfected lysate.
Western Blot
Lane 1: CREB3 transfected lysate ( 40.92 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CREB3 full-length
Host
Human
Theoretical MW (kDa)
40.92
Interspecies Antigen Sequence
Mouse (66); Rat (55)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CREB3 antibody (H00010488-B01) by Western Blots.
SDS-PAGE Gel
CREB3 transfected lysate.
Western Blot
Lane 1: CREB3 transfected lysate ( 40.92 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CREB3
Entrez GeneID
10488GeneBank Accession#
BC009402.2Protein Accession#
-Gene Name
CREB3
Gene Alias
LUMAN, LZIP, MGC15333, MGC19782
Gene Description
cAMP responsive element binding protein 3
Omim ID
606443Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element, an octameric palindrome. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000021348|basic leucine zipper protein|cyclic AMP response element (CRE)-binding protein/activating transcription factor 1|transcription factor LZIP-alpha
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Interactome
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Pathway
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Disease
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